DCU Home | Our Courses | Loop | Registry | Library | Search DCU
<< Back to Module List

Module Specifications.

Current Academic Year 2024 - 2025

All Module information is indicative, and this portal is an interim interface pending the full upgrade of Coursebuilder and subsequent integration to the new DCU Student Information System (DCU Key).

As such, this is a point in time view of data which will be refreshed periodically. Some fields/data may not yet be available pending the completion of the full Coursebuilder upgrade and integration project. We will post status updates as they become available. Thank you for your patience and understanding.

Date posted: September 2024

Module Title Biomolecules & Metabolism
Module Code BE201 (ITS) / BCH1003 (Banner)
Faculty Science & Health School Biotechnology
Module Co-ordinatorPhilip Cummins
Module TeachersKonstantinos Gkrintzalis
NFQ level 8 Credit Rating 5
Pre-requisite Not Available
Co-requisite Not Available
Compatibles Not Available
Incompatibles Not Available
Repeat examination
Array
Description

To equip students with fundamental skills to comprehend and evaluate the spectrum of biological macromolecules essential to maintenance of cell function and respiration.

Learning Outcomes

1. Comprehend the structural and functional complexity of macromolecules (carbohydrates, proteins & lipids)
2. Comprehend the mechanistic nature of a metabolic pathway
3. Evaluate the basic chemistry that underlies the structural properties of different macromolecules
4. Evaluate how disruption in macromolecule function and metabolism can lead to human disease
5. Analyse enzyme performance using basic mathematical models of reaction kinetics



Workload Full-time hours per semester
Type Hours Description
Lecture8Online/F2F: Biological macromolecules - structure, function, regulation.
Lecture8Online/F2F: Cellular metabolism - understanding metabolic pathway mechanisms.
Tutorial10Online/F2F: Lecture review, Q&A, in-class quizzes, gamification strategies.
Independent Study99Course revision and quantitative exercises in enzyme assay kinetics. Individual lecturer interactions and queries. Incentivised participation in virtual study groups.
Total Workload: 125

All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml

Indicative Content and Learning Activities

Content 1 (F2F/Online)
Proteins: Classical amino acid structures, properties, and categories. Non-classical amino acids. Protein structural hierarchy. Protein sequencing and protein purification. Post-translational modifications (phosphorylation, glycosylation, ubiquitination).

Content 2 (F2F/Online)
Carbohydrates: Carbohydrate stereochemistry. Carbohydrates and disease. Complex carbohydrates (e.g. chitin, glycogen, cellulose).

Content 3 (F2F/Online)
Lipids: Fatty acids, glycerides, phospholipids, sphingolipids, steroids, cholesterol, and lipoproteins. Lipids in disease.

Content 4 (F2F/Online)
Enzymes: Enzyme classification, functions and cellular mechanisms of regulation. Quantitative analysis of enzyme catalytic function (enzyme kinetics). Properties of enzyme inhibitors.

Content 5 (F2F/Online)
Metabolism: Bioenergy concepts (RMR, BMR, ATP and NADPH/NADH.) The phosphagen system. Glycolysis, TCA cycle, electron transport chain and oxidative phosphorylation. Anaerobic glycolysis. Glycogenolysis, gluconeogenesis and TG metabolism.

Learning activities (transversal skills, novel pedagogies, critical thinking, problem solving)
In-lecture/tutorial: Digital animations to bring complex figures and concepts to life, real-world scenario-style questions to promote critical thinking around core biochemical principles, quantitative techniques to analyse enzyme performance. Online: Gamification strategies to promote student engagement, understanding and content revision (e.g. biochemistry crosswords, identifying errors deliberately engineered into figures/graphs/scenarios), virtual quizzes to enable formative and summative assessment.

Assessment Breakdown
Continuous Assessment20% Examination Weight80%
Course Work Breakdown
TypeDescription% of totalAssessment Date
Loop QuizFormative online CA to examine understanding of macromolecules (e.g. Online quiz).10%Week 6
Loop QuizFormative online CA to examine understanding of metabolic pathways (e.g. Online quiz).10%Week 12
Reassessment Requirement Type
Resit arrangements are explained by the following categories:
Resit category 1: A resit is available for both* components of the module.
Resit category 2: No resit is available for a 100% continuous assessment module.
Resit category 3: No resit is available for the continuous assessment component where there is a continuous assessment and examination element.
* ‘Both’ is used in the context of the module having a Continuous Assessment/Examination split; where the module is 100% continuous assessment, there will also be a resit of the assessment
This module is category 2
Indicative Reading List

  • Roger Miesfeld & Megan McEvoy: 2017, Biochemistry, 1st Edition, V.W.Norton, 978-0-393-630
Other Resources

None

<< Back to Module List