DCU Home | Our Courses | Loop | Registry | Library | Search DCU

Module Specifications..

Current Academic Year 2023 - 2024

Please note that this information is subject to change.

Module Title Bioprocess Research and Design
Module Code BE214
School School of Biotechnology
Module Co-ordinatorSemester 1: Damien King
Semester 2: Damien King
Autumn: Damien King
Module TeachersPaul Cahill
Brian Freeland
Greg Foley
Denise Harold
David Collins
Yandi Lan
Damien King
NFQ level 8 Credit Rating 5
Pre-requisite None
Co-requisite None
Compatibles None
Incompatibles None
None
Description

In this module the student will undertake an in-depth investigation into oxygen transfer in a bioreactor. Each student will be supplied with a detailed dataset on dissolved oxygen data, as well as cell counts, for a bench scale culture of the yeast Kluyveromyces. The challenge will be to quantify oxygen uptake rates and mass transfer rates while relating these phenomena to cell counts. Students will be expected to be able to draw on what they have learned in BE215 and apply it to the current challenge. On completion of the data analysis the student will write a coherent report detailing their overall approach and in a logical sequence.

Learning Outcomes

1. Analyze experimental data in a critical and creative manner
2. Devise methods for evaluating model parameters by fitting the model to experimental data
3. Use the dynamic simulation package, Berkeley Madonna, to interpret experimental data
4. Produce a coherent laboratory report detailing the outcomes of the research in a logical sequence.
5. Produce high quality graphs of experimental data



Workload Full-time hours per semester
Type Hours Description
Online activity4Week 1 Introduction to module and study of background materials.
Online activity4Weeks 2 and 3. Preliminary analysis of experimental data and production of graphs for first assignment.
Online activity4Weeks 4 and 5: completion of analysis on the relation between cell counts and oxygen uptake rate.
Online activity4Weeks 6 and 7 Write Berkeley Madonna code to model complete oxygen transfer process
Online activity4Weeks 8 and 9; Fit Berkeley Madonna code to the experimental data and tabulate OUR and kla data
Online activity8Weeks 10 and 11. Produce written report.
Online activity97independent leanring and study
Total Workload: 125

All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml

Indicative Content and Learning Activities

Assessment Breakdown
Continuous Assessment100% Examination Weight0%
Course Work Breakdown
TypeDescription% of totalAssessment Date
AssignmentProduce high quality graphs of experimental data (week 2)10%n/a
AssignmentSubmit an analysis of oxygen uptake rates based on the dissolved oxygen data (week 3)20%n/a
AssignmentSubmit an analysis of the relation between oxygen uptake rates and cell counts and represent that relationship graphically (Week 5)10%n/a
AssignmentWrite Berkeley Madonna code to simulate the oxygen uptake/transfer experiment, incorporating an IF statement where appropriate (week 7)15%n/a
AssignmentFit the Berkeley Madonna code to the experimental data and work out the oxygen uptake rate and the kLa for each run. Tabulate the results. (week 9)15%n/a
AssignmentProduce a written report containing an Abstract, an introduction, illustrative raw data and key results presented in a logical sequence. (week 11)30%n/a
Reassessment Requirement Type
Resit arrangements are explained by the following categories;
1 = A resit is available for all components of the module
2 = No resit is available for 100% continuous assessment module
3 = No resit is available for the continuous assessment component
This module is category 1
Indicative Reading List

    Other Resources

    None
    Programme or List of Programmes
    BPBSc in Bioprocessing
    Archives:

    My DCU | Loop | Disclaimer | Privacy Statement