Module: Computational Biology

Module Specifications..

Current Academic Year 2023 - 2024

Please note that this information is subject to change.

Module Title	Computational Biology
Module Code	BE250
School	School of Biotechnology
Module Co-ordinator	Semester 1: Denise Harold Semester 2: Denise Harold Autumn: Denise Harold
Module Teachers	Denise Harold Linda Holland
NFQ level	8	Credit Rating	5
Pre-requisite	None
Co-requisite	None
Compatibles	None
Incompatibles	None

None

Description

Learning Outcomes

1. Understand the process of genome annotation; access biological data from different genome browsers and databases
2. Determine the linkage disequilibrium structure of a genetic locus
3. Perform a genetic association analysis
4. Design PCR primers
5. Estimate homology using computational methods
6. Retrieve sequence data and calculate multiple sequence alignments
7. Work at the command line on Linux

*Type*	*Hours*	*Description*
Workload	Full-time hours per semester
Lecture	24	Computer Practicals
Independent Study	101	No Description
Total Workload: 125

All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml

Indicative Content and Learning Activities

Introduction to genome annotation and the available genome bowsers.

Understanding data formats.

Efficient use of biological databases.

Appropriate statistical analysis of a genetic association study.

Designing PCR primers.

Database search algorithms and statistics.

Multiple sequence alignment.

Linux command-line

Assessment Breakdown
Continuous Assessment	100%	Examination Weight	0%

Type	Description	% of total	Assessment Date
Course Work Breakdown
Loop Quiz	Formative assessments addressing all learning outcomes	20%	As required
In Class Test	Summative assessment: end of semester in-class test	80%	Sem 2 End

Reassessment Requirement Type
Resit arrangements are explained by the following categories; 1 = A resit is available for all components of the module 2 = No resit is available for 100% continuous assessment module 3 = No resit is available for the continuous assessment component
This module is category 2

Indicative Reading List

Other Resources

None

Programme or List of Programmes

GCB	BSc in Genetics & Cell Biology

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