Module Specifications.
Current Academic Year 2024 - 2025
All Module information is indicative, and this portal is an interim interface pending the full upgrade of Coursebuilder and subsequent integration to the new DCU Student Information System (DCU Key).
As such, this is a point in time view of data which will be refreshed periodically. Some fields/data may not yet be available pending the completion of the full Coursebuilder upgrade and integration project. We will post status updates as they become available. Thank you for your patience and understanding.
Date posted: September 2024
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Repeat examination Reassessment will consist of 100% exam |
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Description The purpose of this module is to help students build on their understanding of advanced concepts of cell biology, focusing on structure and function of proteins, lipids and extracellular vesicles; signaling pathways, cell cycle and cellular-cross talk with immune cells. Students will gain insight into dysregulation of cellular processes which can lead to diseases such as cancer and diabetes. They will also focus on tools (particularly lipidomics, proteomics, extracellular vesicles, targeted therapies) used for advancing molecular medicine, disease diagnosis and treatment. | |||||||||||||||||||||||||||||||||||||||||||
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Learning Outcomes 1. Value why lipids and extracellular vesicles are considered a new platform for drug delivery, biomarker discovery and future cancer therapies. 2. Describe the functional characteristics of human pancreatic beta cells and evaluate the most promising sources of new beta cells for functional replacement in Type 1 diabetes. 3. Discuss the advancement in proteomic/mass spec methods to detect specific proteins in biological samples 4. Define the molecules, cell types and pathways that uniquely distinguish the cells in the body including those of the immune system 5. Knowledge of molecular, genomic and cellular processes of immunological and cancer diseases 6. Identify and discuss the cell dysregulations that lead to the hallmarks of cancer | |||||||||||||||||||||||||||||||||||||||||||
All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml |
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Indicative Content and Learning Activities
Cellular ImmunologyInnate & adaptive immunity, Complement, B cells, T Cells, macrophagesCellular DiseasesCancer cell biology, interactions between tissue cellular systems (vascular and immune cells). Immune mechanisms in disease pathogenesis. Lipid Biomarkers in cancer and diabetesLipids in Cell BiologyCellular compartments of common biological lipids; Lipid movements into and out of cells; Modern Lipid analysis Methods; LipidomicsPancreatic beta cell biologyProcessing of Proinsulin; Secretion of insulin; Post insulin receptor binding events in target tissues; Beta cell replacement with allogeneic, xenogeneic pancreatic islets, expanded beta cells, embryonic or induced pluripotent stem cell-derived beta cells; Functionality criteria & analytical methods. | |||||||||||||||||||||||||||||||||||||||||||
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Indicative Reading List
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Other Resources None | |||||||||||||||||||||||||||||||||||||||||||