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Module Specifications..

Current Academic Year 2023 - 2024

Please note that this information is subject to change.

Module Title Immunology and Immunoanalysis
Module Code BE433
School School of Biotechnology
Module Co-ordinatorSemester 1: Christine Loscher
Semester 2: Christine Loscher
Autumn: Christine Loscher
Module TeachersPaul Cahill
Paula Meleady
Christine Loscher
Denise Harold
Michael Freeley
Linda Holland
NFQ level 8 Credit Rating 5
Pre-requisite None
Co-requisite None
Compatibles None
Incompatibles None

This purpose of this module is to provide a detailed understanding of the theory and applications of advanced aspects of immunology. Students will be given an in depth insight into the advantages and limitations of immunoanalytical approaches in clinical, industrial and research situations.

Learning Outcomes

1. Explain the molecular factors that confer immunogenicity to antigens
2. Describe in detail the cellular components involved generating immunity
3. Discuss in detail the methods used to produce antibodies and their appropriate applications
4. Discuss how antibody-based therapy can be used to treat human disease
5. Describe aspects of immunoanalysis including cytometry, immuno-cytochemistry, sensors and antibody-based targeting of ligands
6. Outline the importance of assay validation and research ethics

Workload Full-time hours per semester
Type Hours Description
Lecture24No Description
Seminars2No Description
Tutorial4No Description
Independent Study95No Description
Total Workload: 125

All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml

Indicative Content and Learning Activities

The Process of antibody production at the cellular level; Intrinsic and extrinsic factors that influence antigenicity; Detailed account of B-cell stimulation; Antigen processing within the B-cell; The function and structure of the major histocompatibility antigens (MHC); The interaction of B-cells and T-cells; Genetic control of the immune response; Latest advances in understanding self, and non-self immune responses.

Methods of antibody production (in detail) including polyclonal, monoclonal, bifunctional, multifunctional, genetic methods and production of antibody-derived fragments; Genetics of antibody production and phage display; Reshaped, chimaeric and human antibodies-production and applications; Use of antibodies in cancer including diagnosis,imaging and treatment; Production and application of conjugates used for the generation of antibodies and in immunoanalysis, Detailed account of immunocytochemistry and its applications;Introduction to next generation diagnostic devices.

Assessment Breakdown
Continuous Assessment100% Examination Weight0%
Course Work Breakdown
TypeDescription% of totalAssessment Date
Reassessment Requirement Type
Resit arrangements are explained by the following categories;
1 = A resit is available for all components of the module
2 = No resit is available for 100% continuous assessment module
3 = No resit is available for the continuous assessment component
This module is category 1
Indicative Reading List

  • Ivan M. Roitt, Seamus J. Martin, Peter J. Delves, Dennis Burton,: 0, Roitt's Essential Immunology, 978-1-4051-3603-7
  • Kenneth M. Murphy, Paul Travers, Mark Walport: 2008, Janeway's immunobiology, Garland Science, New York, 978-0-8153-4123-9
Other Resources

Programme or List of Programmes
AFUAge Friendly University Programme
BSSAStudy Abroad (DCU Business School)
BSSAOStudy Abroad (DCU Business School)
BTBSc in Biotechnology
GCBBSc in Genetics & Cell Biology
HMSAStudy Abroad (Humanities & Soc Science)
HMSAOStudy Abroad (Humanities & Soc Science)
IESAStudy Abroad (Institute of Education)
IESAOStudy Abroad (Institute of Education)
SHSAStudy Abroad (Science & Health)
SHSAOStudy Abroad (Science & Health)
Date of Last Revision18-FEB-10

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