Module Specifications..
Current Academic Year 2023 - 2024
Please note that this information is subject to change.
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Description The aim of this module is to provide students with a critical overview of the challenges in administering biopharmaceuticals and strategies for overcoming the main delivery barriers. State of the art concepts for successful formulation and delivery of therapeutic peptides, proteins, nucleic acid-based drugs and vaccines will be described. | |||||||||||||||||||||||||||||||||||||||||
Learning Outcomes 1. List the major challenges in delivery of Biopharmaceuticals and explain why advanced delivery systems are needed 2. Describe how protein and peptide injectables may be chemically modified for improved delivery 3. Critically discuss novel non-injectable formulation approaches of peptide and protein drugs 4. Cite clinical trials using chemical and viral vectors for delivery of nucleic acids. 5. Evaluate commercial feasibility of lipid nanoparticles and polymer-based delivery systems for achieving real clinical applications. 6. Explain the role of freeze-drying technology in drug delivery systems | |||||||||||||||||||||||||||||||||||||||||
All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml |
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Indicative Content and Learning Activities
LectureNovel formulation and delivery approaches for peptide and protein injectablesLectureNovel non-injectable formulation approaches of peptides and proteinsLectureChemical vectors and Viral technology for delivery of nucleic acidsLecturePolymer-Based delivery systems for oral and pulmonary delivery of peptides/proteins/nucleic acids. Role of Freeze drying technology in oral delivery systems. | |||||||||||||||||||||||||||||||||||||||||
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Indicative Reading List
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Other Resources None | |||||||||||||||||||||||||||||||||||||||||
Programme or List of Programmes | |||||||||||||||||||||||||||||||||||||||||
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