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Module Specifications.

Current Academic Year 2024 - 2025

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Date posted: September 2024

Module Title Fundamentals of Bioreaction Engineering
Module Code BE515 (ITS) / BTE1024 (Banner)
Faculty Science & Health School Biotechnology
Module Co-ordinatorDavid Collins
Module Teachers-
NFQ level 9 Credit Rating 5
Pre-requisite Not Available
Co-requisite Not Available
Compatibles Not Available
Incompatibles Not Available
None
Array
Description

The aim of this module is to introduce students to the multi-disciplinary nature of biotechnology and how bioprocesses are planned, organized and how they develop from basic cell structure and function through bioreactors to DSP. The objective is to enable a comprehension of both the concepts and language of biotechnology, to enable communication between people working in the different stages of a bioprocess, from management to form filling. The module also forms the basis for more advanced modules in Principles of Microbial and Animal Cell Culture and Protein Purification/Bioseparations.

Learning Outcomes

1. Communicate what Biotechnology and Bioprocesses are
2. Grasp the problems of containment and process security
3. Decide how to choose the correct cell line (or part thereof) for a desired product
4. Demonstrate an understanding of how this choice affects the whole process development - USP and DSP.
5. Discuss the basics of bioreactors and bioprocess engineering
6. Design integrated bioprocesses for production of bioethanol to recombinant human proteins.



Workload Full-time hours per semester
Type Hours Description
Lecture16No Description
Independent Study109No Description
Total Workload: 125

All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml

Indicative Content and Learning Activities

Fundamentals of Bioreaction Processes
The content of the module comprises the following: a definition of Biotechnology, Integrated Bioprocessing, What a Bioprocess is, Description of a Range of Bioproducts, Differences between Bioprocesses and Chemical Processes, Containment, The Living World and Description of Types of Cellular Systems and Parts thereof (e.g. enzymes and bioconversions) which are used in Bioprocesses, Cell Structure and Choice of Production Cell Line, Bioprocess Design and Operation, Nutritional Requirements and Medium Optimization, Choice of Bioreactor, Suspension versus Immobilized Cells, Cell Recycle Systems, Introduction to Bioprocess Monitoring/ Control and DSP.

Assessment Breakdown
Continuous Assessment100% Examination Weight0%
Course Work Breakdown
TypeDescription% of totalAssessment Date
Reassessment Requirement Type
Resit arrangements are explained by the following categories:
Resit category 1: A resit is available for both* components of the module.
Resit category 2: No resit is available for a 100% continuous assessment module.
Resit category 3: No resit is available for the continuous assessment component where there is a continuous assessment and examination element.
* ‘Both’ is used in the context of the module having a Continuous Assessment/Examination split; where the module is 100% continuous assessment, there will also be a resit of the assessment
This module is category 1
Indicative Reading List

  • Donald & Judith G. Voet: 1995, Biochemistry, 2nd Edition, John Wiley & Sons,
  • James E. Bailey: 1986, Biochemical Engineering Fundamentals:, McGraw-Hill Education,
Other Resources

None

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