Module: Fundamental and Applied Immunology

Module Specifications..

Current Academic Year 2023 - 2024

Please note that this information is subject to change.

Module Title	Fundamental and Applied Immunology
Module Code	BE519
School	School of Biotechnology
Module Co-ordinator	Semester 1: Michael Freeley Semester 2: Michael Freeley Autumn: Michael Freeley
Module Teachers	Paul Cahill Denise Harold Michael Freeley
NFQ level	9	Credit Rating	5
Pre-requisite	None
Co-requisite	None
Compatibles	None
Incompatibles	None

None

Description

Module aims: The purpose of this module is to provide a detailed understanding of the innate and adaptive immune systems in protecting the host against pathogens and microorganisms. Students will subsequently learn how the immune system can be manipulated for disease recognition, particularly in relation to vaccine production and cancer. The module will also provide a comprehensive overview of the production, manipulation and purification of antibodies for diagnostic, biomedical and therapeutic applications.

Learning Outcomes

1. Compare and contrast the cells and components of the innate and adaptive immune systems.
2. Describe how the immune system and immune responses have been exploited for the development of vaccines and cancer.
3. Describe in detail the methods used to produce antibodies and antibody fragments in the laboratory.
4. Identify applications of antibodies and antibody fragments for research, diagnostic and therapeutic applications.
5. Describe several different types of immunoassays and select the most appropriate immunoassay to detect/quantify a particular antigen.
6. Discuss how antibody-based therapy can be used to treat human disease.

*Type*	*Hours*	*Description*
Workload	Full-time hours per semester
Lecture	24	12 lectures
Tutorial	5	5 tutorials
Assignment Completion	41	Assignment on T-cell therapies for cancer
Independent Study	55	No Description
Total Workload: 125

All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml

Indicative Content and Learning Activities

Fundamental and Translational Immunology
The Innate Immune System; The Adaptive Immune System - T-cells; T-cell therapies; CAR T-cells; The Adaptive Immune System - B-cells; Vaccines; Antibody Production; Antibodies and Immunoassays; Therapeutic Antibodies Part 1; Therapeutic Antibodies Part 2.

Assessment Breakdown
Continuous Assessment	100%	Examination Weight	0%

Type	Description	% of total	Assessment Date
Course Work Breakdown
In Class Test	In Class Test	50%	Other
Assignment	An assignment based on an immunology topic.	50%	n/a

Reassessment Requirement Type
Resit arrangements are explained by the following categories; 1 = A resit is available for all components of the module 2 = No resit is available for 100% continuous assessment module 3 = No resit is available for the continuous assessment component
This module is category 1

Indicative Reading List

Janeway: 2012, Janeway's Immunobiology, 8th,
Wild: 2013, The Immunoassay Handbook, Fourth Edition: Theory and applications of ligand binding, ELISA and related techniques., 4, 978-008097037

Other Resources

None

Programme or List of Programmes

AMPD	PhD
AMPM	MSc
AMPT	PhD-track
BTPD	PhD
BTPM	MSc
BTPT	PhD-track
CHPD	PhD
CHPM	Master of Science
CHPT	PhD-track
HHPD	PhD
HHPM	MSc
HHPT	PhD-track
MDPM	MSc in Diagnostics & Precision Medicine
NSPD	PhD
NSPM	MSc
NSPT	PhD-track
PHPD	PhD
PHPM	MSc
PHPT	PhD-track
PYPD	PhD
PYPM	Master of Science
PYPT	PhD-track
SSPD	PhD
SSPM	MSc
SSPT	PhD-track

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