Module: Animal Cell Culture Technology

Module Specifications..

Current Academic Year 2023 - 2024

Please note that this information is subject to change.

Module Title	Animal Cell Culture Technology
Module Code	BE582
School	School of Biotechnology
Module Co-ordinator	Semester 1: Finbarr O'Sullivan Semester 2: Finbarr O'Sullivan Autumn: Finbarr O'Sullivan
Module Teachers	Paul Cahill Brian Freeland Dermot Walls Finbar O'Sullivan Finbarr O'Sullivan Denise Harold David Collins Jonathan Cawley
NFQ level	9	Credit Rating	5
Pre-requisite	None
Co-requisite	None
Compatibles	None
Incompatibles	None

None

Description

The aim of this module is to give students an understanding of the role of cell culture in bioprocessing engineering. It will outline the basic cellular processes that are of relevance to bioprocessing and provide information about the key criteria to be considered for scale-up of a process.

Learning Outcomes

1. Gain critical awareness of the different types of cell culture technologies.
2. Gain a systematic understanding of the criteria for consideration for scale up of cell culture.
3. Gain advanced knowledge to identify the appropriate cell model for a large scale process.
4. Gain critical awareness of recent developments in cell and tissue engineering.
5. Gain a systematic understanding to identify key criteria for a successful cell bank.

*Type*	*Hours*	*Description*
Workload	Full-time hours per semester
Lecture	16	Asynchronous/synchronous/in-person lectures.
Independent Study	69	Reference to reading material
Assignment Completion	40	Complete assignment as directed.
Lecture	16	Asynchronous/synchronous/in-person lectures.
Independent Study	69	Reference to reading material.
Assignment Completion	40	Complete assignment as directed.
Total Workload: 250

All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml

Indicative Content and Learning Activities

Basic Cell Biology

Intro to Cell Culture

Types of Tissue culture

Cell Banking

Cell Freezing

Growing Cell - culture conditions

Cell adhesion

Cell cycle and cell proliferation

Cell transformation

Scale-up - batch culture versus continuous culture

Monolayer culture versus suspension culture

3D culture

Stem cells

Proteomic technology

Microarray technology

Assessment Breakdown
Continuous Assessment	100%	Examination Weight	0%

Type	Description	% of total	Assessment Date
Course Work Breakdown
Loop Quiz	This loop quiz will consist of a series of problem- or challenge-based MCQs to address the students' critical understanding of the curriculum by MCQs that specifically address the students' knowledge of one specific area and use it in another area; sample questions will be provided to students in advance of the exam.	40%	Week 10
Essay	The students will be asked to critically address a specific question in a concise manner through submission of a short essay (~1500 words). The assignment will be due in week 13.	60%	Sem 1 End

Reassessment Requirement Type
Resit arrangements are explained by the following categories; 1 = A resit is available for all components of the module 2 = No resit is available for 100% continuous assessment module 3 = No resit is available for the continuous assessment component
This module is category 1

Indicative Reading List

R. Ian Freshney: 2016, Culture of Animal Cells, 7th Edition, Wiley,
John R. W. Masters: 2000, Animal Cell Culture, Third Edition, Oxford,

Other Resources

None

Programme or List of Programmes

GCBE	Graduate Cert in Bioprocess Engineering
GCBPT	Graduate Certificate in Biotherapeutics
GDBE	Graduate Dip in Bioprocess Engineering
GDBPT	Graduate Diploma in Biotherapeutics
MBPT	MSc in Biotherapeutics
MSBE	MSc in Bioprocess Engineering
SMPSC	Single Module Prof. Science and Health

Date of Last Revision

17-JAN-12

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