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Module Specifications..

Current Academic Year 2023 - 2024

Please note that this information is subject to change.

Module Title Bioreactor Design, Modelling & Monitoring
Module Code BE584
School School of Biotechnology
Module Co-ordinatorSemester 1: Yandi Lan
Semester 2: Yandi Lan
Autumn: Yandi Lan
Module TeachersPaul Cahill
Brian Freeland
Denise Harold
David Collins
Yandi Lan
NFQ level 9 Credit Rating 5
Pre-requisite None
Co-requisite None
Compatibles None
Incompatibles None
None
Description

The aim of this module is to further students’ grasp of the complex interactions between the reaction conditions seen in practical bioreactors and the physiological responses expressed by microbial cells. This module deals with the engineering science of bioreactor design, of the selection and sizing of equipment to perform specific bioreaction tasks, the reaction conditions that can be monitored and manipulated in order to optimise bioreactions, and the data that can be collected and used to model the processes. Students will be introduced to modelling of bioreaction processes under ideal and non-ideal conditions.

Learning Outcomes

1. Explain the principles involved in the classification of bioreactors
2. Assess the suitability of bioreactor configurations for a given process; rationalise the choice of bioreactor design
3. Distinguish between the different types of mathematical models applied to microbial or animal cell bioreactors (Structured / Unstructured; Segregated / Non-Segregated)
4. Apply basic kinetic models to batch, fed-batch and continuous bioreactors
5. Apply basic principles of mass and energy conservation to analyse bioreactor systems
6. Analyze and interpret experimental data from bioreactors, predict and monitor bioreactor operation



Workload Full-time hours per semester
Type Hours Description
Lecture16No Description
Independent Study109No Description
Total Workload: 125

All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml

Indicative Content and Learning Activities

Classification and configuration of bioreactors

Bioreactor operation: sterilization, inoculation, sampling, feeding

The basic kinetic models for biological growth

Kinetic models for enzyme reactors (free & immobilized)

Instrumentation and Control Strategies

Assessment Breakdown
Continuous Assessment100% Examination Weight0%
Course Work Breakdown
TypeDescription% of totalAssessment Date
Reassessment Requirement Type
Resit arrangements are explained by the following categories;
1 = A resit is available for all components of the module
2 = No resit is available for 100% continuous assessment module
3 = No resit is available for the continuous assessment component
This module is category 1
Indicative Reading List

  • Doran, P.: 1995, Bioprocess Engineering Principles, Academic Press,
  • Nielsen, J. & Villadsen, J.: 1994, Bioreaction Engineering Principles, Plenum Press,
  • Bailey J.E. & Ollis D.F.: 1986, Biochemical Engineering Fundamentals, 2nd Ed., McGraw-Hill,
Other Resources

None
Programme or List of Programmes
AMPDPhD
AMPMMSc
AMPTPhD-track
BTPDPhD
BTPMMSc
BTPTPhD-track
CHPDPhD
CHPMMaster of Science
CHPTPhD-track
GCBEGraduate Cert in Bioprocess Engineering
GDBEGraduate Dip in Bioprocess Engineering
HHPDPhD
HHPMMSc
HHPTPhD-track
MSBEMSc in Bioprocess Engineering
NSPDPhD
NSPMMSc
NSPTPhD-track
PHPDPhD
PHPMMSc
PHPTPhD-track
PYPDPhD
PYPMMaster of Science
PYPTPhD-track
SMPSCSingle Module Prof. Science and Health
SSPDPhD
SSPMMSc
SSPTPhD-track
Date of Last Revision10-MAR-11
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