Module: Organic Chemistry

Module Specifications.

Current Academic Year 2024 - 2025

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Date posted: September 2024

Module Title	Organic Chemistry
Module Code	CS204 (ITS) / CHM1010 (Banner)
Faculty	Science & Health	School	Chemical Sciences
Module Co-ordinator	Hasim Ibrahim
Module Teachers	Emma Coyle, Nessan Kerrigan, Patrick O'Malley
NFQ level	8	Credit Rating	5
Pre-requisite	Not Available
Co-requisite	Not Available
Compatibles	Not Available
Incompatibles	Not Available

None
Array

Description

To develop competence in the use of chemical structures and reaction schemes. To develop chemical intuition. To develop an understanding and familiarity with mechanistic concepts. To develop problem-solving skills. To develop the theoretical and conceptual background for laboratory work. To develop an appreciation of the industrial importance of organic chemistry and of the contribution of organic chemistry to society.

Learning Outcomes

1. Describe the main electrophillic substitution reactions of benzene.
2. Predict the location of disubstitution of aromatic rings.
3. Assign R,S stereochemistry
4. Sketch and explain the more stable conformers of substituted cyclohexane.
5. Distinguish between Nucleophilic substitution reactions SN1 or SN2, and outline the mechanism involved.Similiarly consider Electrophilic substitutions E1, E2.
6. Illustrate mechanisms involved, and products obtained, from reactions addressed on the course, such as Aldol condensation, Claisen condensation.

*Type*	*Hours*	*Description*
Workload	Full-time hours per semester
Lecture	36	No Description
Independent Study	89	No Description
Total Workload: 125

All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml

Indicative Content and Learning Activities

ORGANIC FUNCTIONAL GROUPS
Review of their chemistry.

STEREOCHEMISTRY:
Cyclohexane conformational analysis: axial/equatorial positions; chair-chair interconversions; geometrical isomerism and conformational free energies in substituted cyclohexanes; decalins/steroids; hexoses. Chirality: optical activity; polarimetry; centre of chirality; enantiomers; racemates and resolution; several chiral centres; diastereomers; relative and absolute configuration; R- and S- nomenclature; deficiencies of D- and L-nomenclature.

MECHANISMS OF NUCLEOPHILIC DISPLACEMENT:
Kinetics and mechanism; transition state; the SN1 and SN2 processes; structural factors; optical isomerism, configuration and mechanism; solvent effects; Similiarly consider Electrophilic Substitutions E1 and E2.

CARBANION/ENOLATE CHEMISTRY:
Relative acidities of C-H bonds in differing molecular environments; resonance stabilisation; effect of a second stabilising group; Aldol condensation; Claisen condensation and its variants; ethyl acetoacetate, diethyl malonate and ethyl cyanoacetate; synthetic applications of active methylene compounds.

AROMATIC CHEMISTRY:
Benzene structure and electrophilic substitution reactions (nitration, halogenation, sulphonation,alkylation, acylation, metallation).Substituted benzenes: electrophilic substitution reactions of substituted benzene systems; rationalisation of activating and directive effects; survey of the chemistry of substituted benzenes in terms of sources, electrophilic substitution reactions and substituent chemistry - alkylbenzenes; nitrobenzenes; aromatic amines; diazonium salts; phenols; aryl halides (excluding nucleophilic aromatic substitution); aromatic carbonyl compounds.Aromaticity: the Hückel (4n+2) rule; polycyclic aromatics and their chemistry; introduction to annulenes and heteroaromatic systems.

Assessment Breakdown
Continuous Assessment	20%	Examination Weight	80%

Type	Description	% of total	Assessment Date
Course Work Breakdown
Written Exam	n/a	20%	n/a

Reassessment Requirement Type
Resit arrangements are explained by the following categories: Resit category 1: A resit is available for both* components of the module. Resit category 2: No resit is available for a 100% continuous assessment module. Resit category 3: No resit is available for the continuous assessment component where there is a continuous assessment and examination element.
* ‘Both’ is used in the context of the module having a Continuous Assessment/Examination split; where the module is 100% continuous assessment, there will also be a resit of the assessment
This module is category 3

Indicative Reading List

Brown LeMay, Bursten, Langford,Sagatys,Duffy: 0, Cheistry The Central Science, Pearson,

Other Resources

None