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Module Specifications..

Current Academic Year 2023 - 2024

Please note that this information is subject to change.

Module Title Bioanalysis Techniques - level 3 laboratory
Module Code PS356
School School of Physical Sciences
Module Co-ordinatorSemester 1: Jennifer Gaughran
Semester 2: Jennifer Gaughran
Autumn: Jennifer Gaughran
Module TeachersTony Cafolla
Jens Ducree
Jennifer Gaughran
NFQ level 8 Credit Rating 7.5
Pre-requisite None
Co-requisite None
Compatibles None
Incompatibles None

Module Aims: 1. To allow students to learn about various analysis techniques used in biological testing and monitoring with particular focus on techniques that can be incorporated in microfluidic systems. 2. To develop students' understanding and capability to use statistical data analytics techniques effectively. 3. To develop students' advanced measurement skills and good laboratory practice by doing general physics laboratories.

Learning Outcomes

1. Discuss the physical principles involved in biological analysis techniques, in terms of their usefulness for identifying biological markers, including nucleic acid testing, immunoassays and single-cell analysis. Identify and discuss viability of different fabrication technologies in microfluidic systems. Solve related problems.
2. Design 3D biomedical systems using CAD drawing software.
3. Carry out in the lab experimental measurements using various measurements devices and applying the suitable error analysis.
4. Identify the physical principles involved in the laboratory experiments and discuss them in the context of their applications.
5. Apply safe laboratory practice.
6. Write reports on a scientific experimentation.

Workload Full-time hours per semester
Type Hours Description
Lecture24Lectures on Bioanalysis Techniques
Laboratory80Laboratory work on general physics and biodesign
Independent Study83.5Independent study and report writing
Total Workload: 187.5

All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml

Indicative Content and Learning Activities

Introduction to biological fluids, cell biology and cell culturing methods.

Bioanalysis systems
Introduction to systems used for bioanalysis e.g. immunoassays, cell-capture, single-cell analysis, nucleic acid testing.

Bioanalytical techniques
Concepts and principles of bioanalytical techniques including PCR, isothermal amplification, ELISA, western blots, mass spectrometry, chromatography and flow cytometry.

Sample preparation
Investigation of sample preparation requirements and basics in cell product analysis including genomics, proteomics and transcriptomic. Discussion of how these techniques can be miniaturised and incorporated into microfluidic systems.

Basics in microfluidic fabrication and testing techniques . Building and testing of microfluidic structures.

Assessment Breakdown
Continuous Assessment100% Examination Weight0%
Course Work Breakdown
TypeDescription% of totalAssessment Date
Report(s)Written reports for general physics labs30%n/a
Report(s)Written reports for biodesign labs30%n/a
Written ExamIn-class terminal assessment of lecture material24%Week 12
PresentationPresentation on bioanalysis technique16%n/a
Reassessment Requirement Type
Resit arrangements are explained by the following categories;
1 = A resit is available for all components of the module
2 = No resit is available for 100% continuous assessment module
3 = No resit is available for the continuous assessment component
This module is category 2
Indicative Reading List

    Other Resources

    Programme or List of Programmes
    PBMBSc Physics with Biomedical Sciences

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