Registry

Module Specifications

Archived Version 2007 - 2008

Module Title	Fundamentals of Bioreaction Processes
Module Code	BE515
School	School of Biotechnology
Online Module Resources
Module Co-ordinator	Professor Ian W. Marison	Office Number	X2 09
Level	5	Credit Rating	5
Pre-requisite	None
Co-requisite	None

Module Aims

The aim of this module is to introduce students to the multi-disciplinary nature of biotechnology and how bioprocesses are planned, organized and how they develop from basic cell structure and function through bioreactors to DSP. The objective is to enable a comprehension of both the concepts and language of biotechnology, to enable communication between people working in the different stages of a bioprocess, from management to form and filling. The module also forms the basis for more advanced modules in Principles of Microbial and Animal Cell Culture and Protein Purification/Bioseparations.

Learning Outcomes

Understand what Biotechnology and Bioprocesses are.
Grasp the problems of containment and process security
Decide how to choose the correct cell line (or part thereof) for a desired product.
Understand how this choice affects the whole process development- USP and DSP.
Comprehend the basics of bioreactors and bioprocess engineering
Design integrated bioprocesses for production of bioethanol to recombinant human

Indicative Time Allowances
	Hours
Lectures	18
Tutorials
Laboratories	2
Seminars
Independent Learning Time	55

Total	75
Placements
Assignments

NOTE

Assume that a 5 credit module load represents approximately 75 hours' work, which includes all teaching, in-course assignments, laboratory work or other specialised training and an estimated private learning time associated with the module.

Indicative Syllabus

The content of the module comprises the following:

A definition of Biotechnology, Integrated Bioprocessing,

What a Bioprocess is, Description of a Range of Bioproducts, Differences between Bioprocesses and Chemical Processes, Containment, The Living World and Description of Types of Cellular Systems and Parts thereof (e.g. enzymes and bioconversions) which are used in Bioprocesses, Cell Structure and Choice of Production Cell Line, Bioprocess Design and Operation, Nutritional Requirements and Medium Optimization, Choice of Bioreactor, Suspension versus Immobilized Cells, Cell Recycle Systems, Introduction to Bioprocess Monitoring/ Control and DSP.

Assessment
Continuous Assessment	100%	Examination Weight	0%

Indicative Reading List

Biochemistry – Donald & Judith G. Voet – 2^nd Edition (1995)/John Wiley & Sons

Biochemical Engineering Fundamentals – James E. Bailey (1986)/McGraw-Hill

Lecturer's Notes

Programme or List of Programmes

SMPSC

Single Module Professional Science

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