Registry
Module Specifications
Archived Version 2019 - 2020
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Description This purpose of this module is to provide a detailed understanding of the theory and applications of advanced aspects of immunology. Students will be given an in depth insight into the advantages and limitations of immunoanalytical approaches in clinical, industrial and research situations. | |||||||||||||||||||||||||||||||||||||||||
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Learning Outcomes 1. Explain the molecular factors that confer immunogenicity to antigens 2. Describe in detail the cellular components involved generating immunity 3. Discuss in detail the methods used to produce antibodies and their appropriate applications 4. Discuss how antibody-based therapy can be used to treat human disease 5. Describe aspects of immunoanalysis including cytometry, immuno-cytochemistry, sensors and antibody-based targeting of ligands 6. Outline the importance of assay validation and research ethics | |||||||||||||||||||||||||||||||||||||||||
All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml |
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Indicative Content and
Learning Activities ImmunologyThe Process of antibody production at the cellular level; Intrinsic and extrinsic factors that influence antigenicity; Detailed account of B-cell stimulation; Antigen processing within the B-cell; The function and structure of the major histocompatibility antigens (MHC); The interaction of B-cells and T-cells; Genetic control of the immune response; Latest advances in understanding self, and non-self immune responses.ImmunoanalysisMethods of antibody production (in detail) including polyclonal, monoclonal, bifunctional, multifunctional, genetic methods and production of antibody-derived fragments; Genetics of antibody production and phage display; Reshaped, chimaeric and human antibodies-production and applications; Use of antibodies in cancer including diagnosis,imaging and treatment; Production and application of conjugates used for the generation of antibodies and in immunoanalysis, Detailed account of immunocytochemistry and its applications;Introduction to next generation diagnostic devices. | |||||||||||||||||||||||||||||||||||||||||
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Indicative Reading List
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Other Resources None | |||||||||||||||||||||||||||||||||||||||||
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