Registry

Module Specifications

Archived Version 2020 - 2021

Module Title
Module Code
School
Online Module Resources
NFQ level	9	Credit Rating	5
Pre-requisite	None
Co-requisite	None
Compatibles	None
Incompatibles	None

Description

Module aims: The purpose of this module is to provide a detailed understanding of the innate and adaptive immune systems in protecting the host against pathogens and microorganisms. Students will subsequently learn how the immune system can be manipulated for disease recognition, particularly in relation to vaccine production. The module will also provide a comprehensive overview of the production, manipulation and purification of antibodies for diagnostic, biomedical and therapeutic applications.

Learning Outcomes

1. Compare and contrast the cells and components of the innate and adaptive immune systems.
2. Describe how the immune system and immune responses have been exploited for the development of vaccines.
3. Describe in detail the methods used to produce antibodies and antibody fragments in the laboratory.
4. Identify applications of antibodies and antibody fragments for research, diagnostic and therapeutic applications.
5. Describe several different types of immunoassays and select the most appropriate immunoassay to detect/quantify a particular antigen.
6. Discuss how antibody-based therapy can be used to treat human disease.

*Type*	*Hours*	*Description*
Workload	Full-time hours per semester
Lecture	20	10 lectures
Assignment Completion	40	Assignment on Vaccines
Independent Study	39	No Description
Tutorial	6	6 tutorials
Assignment Completion	20	Assignment on T-cell therapies for cancer
Total Workload: 125

All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml

Indicative Content and Learning Activities

Fundamental and Translational Immunology
The Innate Immune System; The Adaptive Immune System - T-cells; T-cell therapies; CAR T-cells; The Adaptive Immune System - B-cells; Vaccines; Antibody Production; Antibodies and Immunoassays; Therapeutic Antibodies Part 1; Therapeutic Antibodies Part 2.

Assessment Breakdown
Continuous Assessment	%	Examination Weight	%

Type	Description	% of total	Assessment Date
Course Work Breakdown

Reassessment Requirement
Resit arrangements are explained by the following categories; 1 = A resit is available for all components of the module 2 = No resit is available for 100% continuous assessment module 3 = No resit is available for the continuous assessment component
Unavailable

Indicative Reading List

Janeway: 2012, Janeway's Immunobiology, 8th,
Wild: 2013, The Immunoassay Handbook, Fourth Edition: Theory and applications of ligand binding, ELISA and related techniques., 4, 978-008097037

Other Resources

None

Programme or List of Programmes

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