Registry
Module Specifications
Archived Version 2021 - 2022
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Description The module addresses the important physiochemical properties of various bioactive molecules (both drugs and biologics) and how these molecules impact on physiological systems in vivo The curriculum covers the basic principles of pharmacology and biopharma and examines the mode of action of certain drug and biologics with a particular emphasis on the principles of pharmacokinetics and dynamics – including routes of administration, distribution absorption and excretion. The various pharmacological and biopharma interventions prescribed for various disease including cancer, cardiovascular disease, inflammation and infection (microbial and viral) is covered in detail addition to new emerging targeted therapies | |||||||||||||||||||||||||||||||||||||
Learning Outcomes 1. The physiochemical properties of various bioactive molecules (both drugs and biologics) 2. The basic principles of pharmacology and biopharma - including mode of action of certain drug and biologics, principles of pharmacokinetics and dynamics 3. Pharmacological and biopharma interventions for cancer - anti-neoplastic drugs 4. Pharmacological and biopharma interventions for the treatment of cardiovascular disease - anti-hypertensives, lipid lowering drugs 5. Pharmacological and biopharma interventions for treatment of inflammation - anti-inflammatory drugs 6. Pharmacological and biopharma interventions for treatment of infection- anti-microbial drugs, anti-virals and anti-fungal drugs 7. Emerging targeted therapies for treatment of various disease - gene therapy, cell therapy, siRNA's | |||||||||||||||||||||||||||||||||||||
All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml |
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Indicative Content and
Learning Activities Biological ChemistryImportant Hydrophilic properties of biological molecules - Important Hydrophobic properties ofPharmaceutical ChemistryFactors affecting the dosage of drugs - Routes of administration of drugs - Metabolism of drugs/moleculesBio-pharmaceutical ChemistryIntroduction to the basic principles of Biopharmacology - Examples of Biopharma Protein and Nucleic Acid drugdIntroduction to PharmacogeneticsBasic principles of Pharmacogenetics with an emphasis on genetic variation in Cytochrome P450 systemCancer TherapeuticsImportant pharmaceutical and biopharmaceutical drug classes that interact with the major systems of the human body to treat cancerCardiovascular TherapeuticsImportant drugs and biologics prescribed for the treatment of cardiovascular diseasesInflammation TherapeuticsImportant drugs and biologics prescribed for the treatment of inflammation (acute and chronic) - immunomodulatory drugsAnti-infective TherapeuticsImportant drugs and biologics prescribed for the treatment of infection, bacteria, viral and fungal infections | |||||||||||||||||||||||||||||||||||||
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Indicative Reading List
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Other Resources 45913, Book, Walsh, Gary, John Wiley & Sons, New York, 2003, Biopharmaceuticals: Biochemistry and biotechnology, 2nd edition, Wiley and Sons, New York, https://pharmareview.files.wordpress.com/2015/03/biopharmaceuticals-biochemistry-and-biotechnology-walsh-wiley-2e-2003.pdf, 45914, Website, Richard E. Klabunde, Ph.D., 1999, Cardiovascular Pharmacology Concepts, https://www.cvpharmacology.com, | |||||||||||||||||||||||||||||||||||||
Programme or List of Programmes | |||||||||||||||||||||||||||||||||||||
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