| Module Title |
Introduction to Bioprocess Engineering |
| Module Code |
BTE1031 (ITS: BE580) |
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Faculty |
Biotechnology |
School |
Science & Health |
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NFQ level |
9 |
Credit Rating |
5 |
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Description
The aim of this module is to introduce the Biopharmaceutical and other related industries and their associated processing principles and techniques. The module will expand the students’ knowledge and understanding of bioprocessing in industry, and will improve the students’ analytical abilities and problem solving methodologies in this area. This module also forms a basis for more advanced modules in bioreactors and bioseparations.
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Learning Outcomes
1. Gain systematic understanding to describe in qualitative terms the operation of a variety of upstream and downstream biopharmaceutical process operations. 2. Gain advanced knowledge to manipulate and perform calculations on process variables with particular emphasis on data analysis and evaluation. 3. Gain complex and advanced skills to apply steady and unsteady-state material and energy balance concepts to batch, fed batch and continuous processes. 4. Gain systematic knowledge to perform simple design calculations for a variety of rate-controlled process equipment. 5. Gain critical awareness to evaluate equipment design on the basis of performance for a range of processes.
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| Workload | Full time hours per semester | | Type | Hours | Description |
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| Lecture | 16 | synchronous/a-synchronous/in-person lecture | | Independent Study | 68 | Reference to reading material and preparation for assessments. | | Assignment Completion | 40 | Completion of assignments. | | Assessment Feedback | 1 | Feedback given to students regarding assignment. | | Lecture | 16 | synchronous/a-synchronous/in-person lecture | | Independent Study | 68 | Reference to reading material and preparation for assessments. | | Assignment Completion | 40 | Completion of assignments. | | Assessment Feedback | 1 | Feedback given to students regarding assignments. |
| Total Workload: 250 |
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| Section Breakdown | | CRN | 10172 | Part of Term | Semester 1 | | Coursework | 0% | Examination Weight | 0% | | Grade Scale | 40PASS | Pass Both Elements | Y | | Resit Category | RC1 | Best Mark | N | | Module Co-ordinator | Arul Manikandan | Module Teacher | Brian Freeland, David Collins, Denise Harold, Janosch Heller, Paul Cahill, Yandi Lan |
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| Assessment Breakdown |
| Type | Description | % of total | Assessment Date |
| In Class Test | In class calculations of bioprocesses addressing the students' critical understanding of process variables. | 20% | Week 4 | | Loop Exam | Loop examination including MCQ and calculations of bioprocesses to assess students' critical understanding using engineering methods to solve the bioprocess questions. | 40% | Week 8 | | Assignment | Simulation of bioprocess: students will design their bioprocesses for manufacturing their products, using engineering methods to develop and evaluate the bioprocess. Process design (descriptions and diagrams) and calculations are required in the assessment. | 40% | Week 10 |
| Reassessment Requirement Type |
Resit arrangements are explained by the following categories;
RC1: A resit is available for both* components of the module.
RC2: No resit is available for a 100% coursework module.
RC3: No resit is available for the coursework component where there is a coursework and summative examination element.
* ‘Both’ is used in the context of the module having a coursework/summative examination split; where the module is 100% coursework, there will also be a resit of the assessment
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Pre-requisite |
None
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Co-requisite |
None |
| Compatibles |
None |
| Incompatibles |
None |
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All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml
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Indicative Content and Learning Activities
Upstream & Downstream processes in the biopharmaceutical industry
Engineering calculations - units, variables and dimensional analysis
Steady and unsteady state material and energy balances
Principles and applications of heat transfer
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Indicative Reading List
Books:
- Pauline M. Doran: 2012, Bioprocess Engineering Principles, 2, Academic Press, 9780122208515
- Morris, A.: 2011, Handbook on Material and Energy Balance Calculations in Materials Processing, Wiley, 978-1-118-065
Articles:
- J Posner, P Barrington, T Brier, A Datta-Mannan: 2019, Monoclonal Antibodies: Past, Present and Future, https://doi.org/10.1007/164_2019_323,
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Other Resources
None |
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