Registry
Module Specifications
Archived Version 2010 - 2011
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Description The purpose of this module is to build on the principles of recombinant DNA technology and gene expression introduced in Module BE301. Students will develop a good understanding of how this knowledge has been extended and developed to analyse and manipulate the genomes of plants and humans by gaining knowledge in bacterial-plant interactions, Genetically Modified Organisms, human inheritance and genetic variation of both mendelian and non-mendelian traits. Students are expected to attend lectures and participate in tutorial discussions. | |||||||||||||||||||||||||||||||||||||||||
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Learning Outcomes 1. Describe the biology of bacterial-plant interactions. 2. Explain the techniques used to produce genetically altered plants. 3. Discuss the development and release of genetically modified organisms. 4. Describe the steps involved in identifying human disease genes and explain by giving examples. 5. Discuss the details of the latest technical advances in human genomics. | |||||||||||||||||||||||||||||||||||||||||
All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml |
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Indicative Content and
Learning Activities Genetic Analysis and Manipulation of Plants.Agrobacterium and its interaction with plants. Ti plasmid-based vectors and plant transformation. Plant transformation and microprojectiles. Inheritance and expression of chimeric genes. Insect/viral/herbicide resistant plants. Transgenic plants for the production of recombinant products. GM plants for fuel and food production. GMO release into the environment.Human Molecular Genetics.Human recombination and genetic mapping. Approaches to identifying the genes responsible for monogenic disorders. The latest therapeutic approaches to treating monogenic diseases. An understanding of oligogenic & polygenic inheritance and quantitative & discontinuous traits. How to conduct an association study and utilize the HapMap data. An understanding of linkage disequilibrium. Latest technologies and post-human genome projects. The impact of the environment on the human genome. | |||||||||||||||||||||||||||||||||||||||||
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Indicative Reading List
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Other Resources None | |||||||||||||||||||||||||||||||||||||||||
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