Registry

Module Specifications

Archived Version 2010 - 2011

Module Title	Bioreactor Design, Modelling & Monitoring
Module Code	BE584
School	School of Biotechnology
Online Module Resources
Module Co-ordinator	Dr Jenny Lawler	Office Number	X221
NFQ level	9	Credit Rating	5
Pre-requisite	None
Co-requisite	None
Compatibles	None
Incompatibles	None

Description

The aim of this module is to further students’ grasp of the complex interactions between the reaction conditions seen in practical bioreactors and the physiological responses expressed by microbial cells. This module deals with the engineering science of bioreactor design, of the selection and sizing of equipment to perform specific bioreaction tasks, the reaction conditions that can be monitored and manipulated in order to optimise bioreactions, and the data that can be collected and used to model the processes. Students will be introduced to modelling of bioreaction processes under ideal and non-ideal conditions.

Learning Outcomes

1. Explain the principles involved in the classification of bioreactors
2. Assess the suitability of bioreactor configurations for a given process; rationalise the choice of bioreactor design
3. Distinguish between the different types of mathematical models applied to microbial or animal cell bioreactors (Structured / Unstructured; Segregated / Non-Segregated)
4. Apply basic kinetic models to batch, fed-batch and continuous bioreactors
5. Apply basic principles of mass and energy conservation to analyse bioreactor systems
6. Describe the origin of non-ideal flow behaviour in real reactors and the impact of non-ideal flow effects on process performance, design and modelling
7. Analyze and interpret experimental data from bioreactors, predict and monitor bioreactor operation

*Type*	*Hours*	*Description*
Workload	Full-time hours per semester
Lecture	16	No Description
Independent Study	109	No Description
Total Workload: 125

All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml

Indicative Content and Learning Activities

Classification and configuration of bioreactors

Bioreactor operation: sterilization, inoculation, sampling, feeding

The basic kinetic models for biological growth

Non-ideal flow effects in bioreactors

Instrumentation and Control Strategies

Assessment Breakdown
Continuous Assessment	100%	Examination Weight	0%

Type	Description	% of total	Assessment Date
Course Work Breakdown

Reassessment Requirement
Resit arrangements are explained by the following categories; 1 = A resit is available for all components of the module 2 = No resit is available for 100% continuous assessment module 3 = No resit is available for the continuous assessment component
Unavailable

Indicative Reading List

Doran, P.: 1995, Bioprocess Engineering Principles, Academic Press,
Nielsen, J. & Villadsen, J.: 1994, Bioreaction Engineering Principles, Plenum Press,
Bailey J.E. & Ollis D.F.: 1986, Biochemical Engineering Fundamentals, 2nd Ed., McGraw-Hill,

Other Resources

None

Programme or List of Programmes

GDBE	Graduate Dip in Bioprocess Engineering
MSBE	Master of Science in Bioprocess Engineer

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