Registry

Module Specifications

Archived Version 2022 - 2023

Module Title	Bioreactor Design, Modelling & Monitoring
Module Code	BE584
School	School of Biotechnology
Online Module Resources
Module Co-ordinator	Dr Jenny Lawler	Office Number	X221
NFQ level	9	Credit Rating	5
Pre-requisite	None
Co-requisite	None
Compatibles	None
Incompatibles	None

Description

The aim of this module is to further students’ grasp of the complex interactions between the reaction conditions seen in practical bioreactors and the physiological responses expressed by microbial cells. This module deals with the engineering science of bioreactor design, of the selection and sizing of equipment to perform specific bioreaction tasks, the reaction conditions that can be monitored and manipulated in order to optimise bioreactions, and the data that can be collected and used to model the processes. Students will be introduced to modelling of bioreaction processes under ideal and non-ideal conditions.

Learning Outcomes

1. Explain the principles involved in the classification of bioreactors
2. Assess the suitability of bioreactor configurations for a given process; rationalise the choice of bioreactor design
3. Distinguish between the different types of mathematical models applied to microbial or animal cell bioreactors (Structured / Unstructured; Segregated / Non-Segregated)
4. Apply basic kinetic models to batch, fed-batch and continuous bioreactors
5. Apply basic principles of mass and energy conservation to analyse bioreactor systems
6. Analyze and interpret experimental data from bioreactors, predict and monitor bioreactor operation

*Type*	*Hours*	*Description*
Workload	Full-time hours per semester
Lecture	16	No Description
Independent Study	109	No Description
Total Workload: 125

All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml

Indicative Content and Learning Activities

Classification and configuration of bioreactors

Bioreactor operation: sterilization, inoculation, sampling, feeding

The basic kinetic models for biological growth

Kinetic models for enzyme reactors (free & immobilized)

Instrumentation and Control Strategies

Assessment Breakdown
Continuous Assessment	100%	Examination Weight	0%

Type	Description	% of total	Assessment Date
Course Work Breakdown

Reassessment Requirement
Resit arrangements are explained by the following categories; 1 = A resit is available for all components of the module 2 = No resit is available for 100% continuous assessment module 3 = No resit is available for the continuous assessment component
Unavailable

Indicative Reading List

Doran, P.: 1995, Bioprocess Engineering Principles, Academic Press,
Nielsen, J. & Villadsen, J.: 1994, Bioreaction Engineering Principles, Plenum Press,
Bailey J.E. & Ollis D.F.: 1986, Biochemical Engineering Fundamentals, 2nd Ed., McGraw-Hill,

Other Resources

None

Programme or List of Programmes

AMPD	PhD
AMPM	MSc
AMPT	PhD-track
BTPD	PhD
BTPM	MSc
BTPT	PhD-track
CHPD	PhD
CHPM	Master of Science
CHPT	PhD-track
GCBE	Graduate Cert in Bioprocess Engineering
GDBE	Graduate Dip in Bioprocess Engineering
HHPD	PhD
HHPM	MSc
HHPT	PhD-track
MSBE	MSc in Bioprocess Engineering
NSPD	PhD
NSPM	MSc
NSPT	PhD-track
PHPD	PhD
PHPM	MSc
PHPT	PhD-track
PYPD	PhD
PYPM	Master of Science
PYPT	PhD-track
SMPSC	Single Module Prof. Science and Health
SSPD	PhD
SSPM	MSc
SSPT	PhD-track

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