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Module Aims
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To introduce the student to the unit operation concept in downstream processing. To develop the theory underlying a range of solid-liquid and heat transfer operations, especially those studied in module BE322. To apply theory to the design, analysis and optimisation of these operations. To further develop problem solving skills acquired in modules BE221, BE222 and BE223.
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Learning Outcomes
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The student should be able to:
* Describe in qualitative terms the principles and mode of operation of a range of solid-
liquid and heat transfer processing equipment
* Derive simple design equations for solid-liquid and heat transfer operations
* Use simple theory as a guide for improving the performance of industrial equipment
* Give an account of recent developments in the theory and practice of solid-liquid and
heat transfer operations.
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Indicative Time Allowances
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Hours
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Lectures |
36
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Tutorials |
0
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Laboratories |
0
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Seminars |
0
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Independent Learning Time |
39
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Total |
75
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Placements |
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Assignments |
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NOTE
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Assume that a 5 credit module load represents approximately 75 hours' work, which includes all teaching, in-course assignments, laboratory work or other specialised training and an estimated private learning time associated with the module.
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Indicative Syllabus
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* Introduction: role of downstream
processing in biotechnology
* Dead-end Filtration: constant pressure
operation, factors affecting the specific
cake resistance, filter clogging, filtration
equipment
* Crossflow Membrane Filtration: factors
affecting the flux in batch and continuous
systems, simple mathematical models
* Ultrafiltration: flux theories, batch and
continuous system design, diafiltration
* Fluid Mechanics of particle-fluid systems:
settling velocities, particle Reynolds
number, drag coefficients, concentration
effects
* Centrifugal Separations: Centrifuges,
Cyclones and Hydrocyclones
* Evaporation: single and multiple effects
* Convection Drying
* Spray Drying and Freeze Drying
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| Assessment | | Continuous Assessment | 20% | Examination Weight | 80% |
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Indicative Reading List
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Essential: None
Unit Operations of Chemical Engineering, 6th Edition, W.L McCabe, J.C. Smith and P. Hariott.
(McGraw-Hill 2001)
Bioseparations: Donnstream Processing for Biotechnology. P.A. Belter, E.L. Cussler and W.-S. Hu (Wiley, 1988)
Biochemical Engineering. H.W. Blanch and D.S. Clark (Marcel Dekker, 1997)
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Programme or List of Programmes
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| BSSA | Study Abroad (DCU Business School) |
| BSSAO | Study Abroad (DCU Business School) |
| BT | BSc in Biotechnology |
| ECSA | Study Abroad (Engineering & Computing) |
| ECSAO | Study Abroad (Engineering & Computing) |
| HMSA | Study Abroad (Humanities & Soc Science) |
| HMSAO | Study Abroad (Humanities & Soc Science) |
| SHSA | Study Abroad (Science & Health) |
| SHSAO | Study Abroad (Science & Health) |
| Archives: | |
