Registry
Module Specifications
Archived Version 2014 - 2015
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Description To develop an understanding of the genetic complexity of biological systems To inform students on the current state of understanding of genetic structure and function in prokaryotes and eukaryotes To provide an overview of genetic mechanisms, heredity and evolution | |||||||||||||||||||||||||||||||||||||||||
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Learning Outcomes 1. Discuss the principles of Heredity and describe the current understanding of evolutionary principles 2. Outline the concepts of developmental genetics and explain how a differentiated state develops from an organism s genome. 3. Define the genetic complexity of biological systems and the current state of understanding of genetic structure and function in prokaryotes and eukaryotes 4. Illustrate the principles that underlie genetic technologies | |||||||||||||||||||||||||||||||||||||||||
All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml |
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Indicative Content and
Learning Activities Prokaryotic GeneticsGenomes-definition, size and complexity, circular and linear chromosomes, plasmids Mutation, the basis for diversity-point mutations, deletions, frameshifting, insertions, inversions, phasevariation, reversion, conditional lethal mutants, suppression, complementation, genotype and phenotype, mutagenesis, mutant selection,auxotrophy, the Ames test Recombination and repair-homologous, site specific and illegitimate recombination, transposition, IS elements, transposons, integrons Bacteriophage genetics-bacteriophage l, lysogenic and lytic life cycles, control of lysogeny, other bacteriophages, M13, T4, Gene transfer in bacteria-transformation, discovery, mechanisms, transduction, specialised and generalised, conjugation, the F factor, Hfr and F prime strains, mapping the Escherichia coli genome, R factors, antibiotic resistance, conjugativetransposons, plasmid mobilisationGenetic organisation and regulation-operons and regulons, regulators, repression and activation, the lactose and arabinose operons, post transcriptional regulation, global regulators, quorum sensing Example of genetic structure and function in bacteria-the virulence of Vibrio choleraeEukaryotic GeneticsHeredity - Historical Prospective, Mendelian Genetics, Extensions of Mendelian Genetics Quantitative Genetics, Linkage Crossing Over and Mapping in Eukaryotes Sex Determination and Sex Chromosomes, Extrachromosomal inheritance Chromosome Mutations Variation in Chromosome Number and arrangement. Genetics of Organisms and Populations - Developmental Genetics, Genetics and Cancer, Genetics and Immunity - Genetics and Behaviour, Population Genetics, Evolution. | |||||||||||||||||||||||||||||||||||||||||
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Indicative Reading List | |||||||||||||||||||||||||||||||||||||||||
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Other Resources None | |||||||||||||||||||||||||||||||||||||||||
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