Registry
Module Specifications
Archived Version 2018 - 2019
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Description This module will introduce students to the field of comparative genomics and its many applications and to the field of developmental biology. | |||||||||||||||||||||||||||||||||||||||||
Learning Outcomes 1. Discuss the basic concepts of comparative genomics and developmental biology from both a computational and cellular perspective 2. Describe the process of analysing biological sequence data from databases to statistical methods for analysing/assessing data signal 3. Discuss concepts in molecular evolution 4. Solve problems of gene expression using microArray data and statistical and clustering techniques 5. Discuss the process of cell fate, determination, and specification 6. Illustrate pattern formation | |||||||||||||||||||||||||||||||||||||||||
All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml |
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Indicative Content and
Learning Activities Indicative SyllabusIntroduction to Comparative Genomics, key concepts including homology, orthology and paralogy. Major comparative genomic methods will be dealt with in detail, including Pairwise and multiple alignment methodologies, Probability and Statistical Analysis of Sequence alignments, Databases and mining, Phylogeny reconstruction and problem solving, MicroArray Analysis statistics and clustering methodologies. A brief history of developmental biology. Early key experiments and milestones. Introduction of model organisms such as Xenopus, zebrafish, chick,mouse, Drosophila andC. elegans. Basic stages of development:comparison of model organisms. Focus on Drosophila lifecycle and development. Drosophila developmental genetics- establishmentof body plan: anterior-posterior axis, dorsal-ventral axis. | |||||||||||||||||||||||||||||||||||||||||
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Indicative Reading List
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Other Resources None | |||||||||||||||||||||||||||||||||||||||||
Programme or List of Programmes | |||||||||||||||||||||||||||||||||||||||||
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